| Acronym | Meaning |
| CC | Credit Card Carbon Copy Crowd Control Country Code |
| CCC | Coricidin Cough & Cold (Dextromethorophan or DXM). |
| CCG | Collectible Card Game |
| CCIE | Cisco Certified Internetwork Expert |
| CCL | Couldn’t Care Less |
| CCNA | Cisco Certified Network Associate |
| CCR | Creedence Clearwater Revival (band) |
| CCTV | Closed-Circuit Television |
| CCW | Counterclockwise Carrying a Concealed Weapon |
| CD | Compact Disc Cross Dresser |
| CDC | Cult of the Dead Cow Crudely Drawn Cock |
| CDMA | Code Division Multiple Access (voice/data transmission) |
| CD-RW | Compact Disk Rewritable |
| CLWY | Can’t Live Without You |
| CM | Call Me |
| CMAR | Cry Me A River |
| CMB | Call Me Back |
| CME | Close My Eyes |
| CMEO | Crying My Eyes Out |
| CMH | Cross My Heart |
| CMHO | Cry My Heart Out |
| CMI | Count Me In |
| CMIIW | Correct Me If I’m wrong. |
| CMIYC | Catch Me If You Can |
| CML | Call Me Later |
| CMN | Call Me Now |
| CMOS | Complementary Metal-Oxide Semiconductor |
| CMS | Content Management System |
| CMU | Cracks Me Up |
| CMYK | Cyan, Magenta, Yellow, Key/blacK |
| CNN | Cable News Network |
| CNY | Chinese New Year |
| CO | Commanding Officer Corrections Officer Company Counter Offer |
| COA | Certificate Of Authenticity |
| COD | Cash On Delivery Call Of Duty |
| COL | Crying Out Loud |
| CRB | Criminal Records Bureau (UK) |
| CRBT | Crying Real Big Tears |
| CWTSY | Can’t Wait To See You |
| CWYL | Chat With You Later. |
| CYB | Count Your Blessings |
| CYBI | Can You Believe It? |
| CYDI | Can You Dig It? |
| CYDM | Check Your Direct Messages |
| CYE | Check Your Email |
| CYF | Cross Your Fingers |
| CYL | Catch You Later |
| CYM | Check Your Mail |